Memantine and Postoperative Pain

Stopped early · Phase 4 · Has a placebo group

Conditions studied: Pain

In brief

Memantine is associated with improvement in pain relief after surgery.

Key facts

Study ID

NCT01032759

Run by

Duke University

People needed

77

Starts

2009-12-01

Expected to finish

2015-01-01

Last updated by the study team

2016-03-14

Who can join

Age: 18 and older, up to 75. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Male
• Age 18 to 75 years old

You may not qualify if…

• Chronic pain conditions or taking regular analgesics
• Taking psychotropic medications
• Parkinson's disease
• Narrow-angle glaucoma
• Known gastroduodenal ulcer
• History of seizure disorder
• Renal insufficiency, as defined by serum creatinine greater than 2 mg/dL
• Liver disease, including liver failure, cirrhosis, or acute hepatitis
• Significant coronary vascular disease or cardiac conduction system disease, as noted by ECG or history of cardiac symptoms, or cardiac ejection fraction less than 30%
• American Society of Anesthesiologists (ASA) score of 4 or higher
• Allergy to ketorolac or memantine

Where it is running

• Duke University — Durham, North Carolina, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.