A Reduced Carbohydrate Diet Intervention for Polycystic Ovary Syndrome (PCOS)

Completed · Not applicable

Conditions studied: Polycystic Ovary Syndrome

In brief

Polycystic ovary syndrome (PCOS) affects 5-10% of women of reproductive age, and is associated with infertility, risk for obesity and type 2 diabetes, and impaired quality of life. The elevated insulin characteristic of PCOS is likely to play a major role in its symptoms. Manipulation of dietary carbohydrate quantity and quality (glycemic load; GL) may lower insulin and improve both reproductive and metabolic outcomes. The purpose of this study is to determine if a lower GL diet intervention is more effective than a standard (STD) diet in improving reproductive and metabolic outcomes of women with PCOS in the absence of weight loss.

Key facts

Study ID

NCT01028989

Run by

University of Alabama at Birmingham

People needed

23

Starts

2009-12-01

Expected to finish

2011-08-01

Last updated by the study team

2013-03-15

Who can join

Age: 19 and older, up to 50. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Diagnosed with PCOS
• Body mass index 18.5-35 kg/m2

You may not qualify if…

• Cushing's syndrome
• Type 1 or 2 diabetes
• Self-reported claustrophobia
• Androgenic tumors or adrenal hyperplasia
• Hyperprolactinemia
• Implanted metal items
• Use of metformin or other diabetes drug
• Women using oral contraceptives will not be excluded, but will be required to discontinue use of these agents 3 months prior to testing.

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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