This Study Will Assess the Safety and Tolerability of AZD8418 After Single Increasing Oral Doses

Stopped early · Phase 1 · Has a placebo group

Conditions studied: Healthy

In brief

The main purpose of this study is to assess the safety and tolerability of AZD8418 after single increasing oral doses. Another purpose of this study is to evaluate the pharmacokinetics (also called PK - how the study drug enters and leaves the body and how your body acts on the study drug) of AZD8418. Part B of the study will assess the effect of food on the safety and pharmacokinetics of AZD8418.

Key facts

Study ID

NCT01027234

Run by

AstraZeneca

People needed

40

Starts

2009-11-01

Expected to finish

2010-03-01

Last updated by the study team

2010-05-26

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy male volunteers
• Healthy female volunteers of non-childbearing potential

You may not qualify if…

• History of any clinically significant medical, neurologic, or psychiatric disease (including repeated episodes of major depression) or a disorder which, in the opinion of the Investigator, may either put the volunteer at risk because of participation
• History of severe allergy/hypersensitivity or ongoing allergy/hypersensitivity, as judged by the Investigator, or history of hypersensitivity to drugs with a similar chemical structure or class to AZD8418

Where it is running

• Research Site — Overland Park, Kansas, United States

Full record on ClinicalTrials.gov

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