XLIF® vs. MAS®TLIF for the Treatment of Symptomatic Lumbar Degenerative Spondylolisthesis With or Without Central Stenosis.

Completed

Conditions studied: Spondylolisthesis

In brief

The purpose of this study is to determine differences in the XLIF and TLIF procedures with respect to perioperative variables in adult patients with low-grade symptomatic spondylolisthesis.

Key facts

Study ID

NCT01024699

Run by

NuVasive

People needed

55

Starts

2009-11-01

Expected to finish

2015-02-01

Last updated by the study team

2025-12-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male and female patients who are at least 18 years of age;
• Patients who present with symptomatic Grade I or II degenerative spondylolisthesis at 1 or 2 contiguous lumbar levels between L1 and L5 and are surgical candidates for interbody lumbar fusion surgery; symptoms should include radiculopathy and/or neurogenic claudication with or without back pain;
• Patients who have been unresponsive to at least 6 months of conservative treatments or exhibit progressive neurological symptoms in the face of conservative treatment;
• Patients who understand the conditions of enrollment and are willing to sign an informed consent to participate in the study.

You may not qualify if…

• Patients with lumbar pathologies requiring treatment at more than 2 levels;
• Patients who have had previous lumbar fusion surgery;
• Patients with lytic spondylolisthesis or a defect of the pars interarticularis;
• Patients with radiographic confirmation of Grade IV facet joint disease or degeneration;
• Patients with non-contained or extruded herniated nucleus pulposus

Where it is running

• St. Vincent-Jacksonville — Jacksonville, Florida, United States
• Celebration Florida Hospital — Kissimmee, Florida, United States
• St. Joseph's/Candler Health System — Savannah, Georgia, United States
• Northwest Orthopaedic Specialists, P.S. — Paducah, Kentucky, United States
• Orthopaedic Clinic-Riverside Campus, University of Minnesota — Minneapolis, Minnesota, United States
• Duke University Medical Center — Durham, North Carolina, United States
• The Methodist Hospital — Houston, Texas, United States
• Spine and Sports Institute — Richland, Washington, United States
• Northwest Orthopaedic Specialists, P.S. — Spokane, Washington, United States

Full record on ClinicalTrials.gov

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