Taste Perception and Chronic Disease Risk
Completed
Conditions studied: Cardiovascular Disease, Diabetes, Obesity, Metabolic Syndrome, Aging
In brief
The purpose of the Taste Perception Study is to assess variations in the ability to taste and perceive sensations from various stimuli in younger (18-49 years) and older (50-85 years) volunteers. The study's goal is to determine how these sensations influence what one likes to eat, and what one chooses to eat, and whether there is an association with dietary intake, body composition and chronic disease. Another objective of the study is to determine the association between variations in oral sensations and genes mediating sensory perception and dietary behaviours.
Key facts
- Study ID
- NCT01023906
- Run by
- Tufts University
- People needed
- 90
- Starts
- 2008-07-01
- Expected to finish
- 2010-03-01
- Last updated by the study team
- 2014-05-23
Who can join
Age: 18 and older, up to 85. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- men and women;
- aged 18 to 85 years old;
- free of known chronic disease;
- BMI < 35 kg/ m2.
You may not qualify if…
- BMI ≥ 35 kg/m2;
- renal or liver disease;
- untreated hypertension;
- irritable bowel syndrome;
- malabsorptive, esophageal and gastrointestinal motility disorders;
- chronic pancreatitis, or history of acute pancreatitis within the last year;
- hypothyroidism or hypothyroidism, as defined as screening TSH outside of normal ranges;
- anemia, as defined by screening hematocrit of 34% for women and 38% for men;
- smoking within the past 6 months;
- diabetes;
- fasting glucose ≥ 125 mg/dL;
- pregnancy or breastfeeding;
- history of polycystic ovary syndrome;
- history of autoimmune or other connective tissue disorders associated with chronic inflammation, such as rheumatoid arthritis; alcohol consumption > 7 drinks/ week;
- use of medications known to affect glucose or lipid metabolism;
- established CVD (myocardial infarction, stroke, heart failure, coronary artery bypass, graft, stenosis > 50%, peripheral arterial disease);
- unwillingness to adhere to study protocol;
- weight gain or loss of more than 15 lbs within 6 months prior to enrollment and other abnormal screening laboratory analysis results.
Where it is running
- Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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