Serum Brain Natriuretic Peptide Levels and Pulmonary Hypertension in Pediatric Sickle Cell Patients

Completed

Conditions studied: Pulmonary Hypertension

In brief

The purpose of this study is 1. To determine if Brain natriuretic peptide levels correlates with elevated tricuspid regurgitation flow velocity levels in pediatric patients with sickle cell disease 2. To determine the role of age, gender, steady state hemoglobin and disease type on Brain natriuretic peptide levels and pulmonary hypertension

Key facts

Study ID

NCT01023451

Run by

Akron Children's Hospital

People needed

21

Starts

2009-12-01

Expected to finish

2013-06-01

Last updated by the study team

2014-06-26

Who can join

Age: 7 and older, up to 21. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male and Female any age
• Diagnosis of SCD with PHT on echocardiogram
• Controls must have a diagnosis of sickle cell disease without Pulmonary hypertension, age, gender and disease type match to subjects with pulmonary hypertension
• Parent or Legal guardian willing to sign informed consent form

You may not qualify if…

• Abnormal echocardiograms not related to PHT
• Parent or Legal guardian unwilling or unable to give written informed consent

Where it is running

• Akron Children's Hospital Sickle Cell Clinic — Akron, Ohio, United States

Full record on ClinicalTrials.gov

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