Trial of Late Surfactant for Prevention of Bronchopulmonary Dysplasia

Completed · Phase 3 · Has a placebo group

Conditions studied: Bronchopulmonary Dysplasia

In brief

The purpose of this study is to determine if late doses of Infasurf surfactant given when patients are receiving inhaled nitric oxide will interact to improve surfactant function and increase survival without BPD in treated infants.

Key facts

Study ID

NCT01022580

Run by

Roberta Ballard

People needed

511

Starts

2010-01-01

Expected to finish

2016-01-01

Last updated by the study team

2021-05-13

Who can join

Age: 0 and older, up to 0. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• <=28 0/7 weeks gestational age
• Day of life 7-14
• Intubated and mechanically ventilated
• Plan to treat with inhaled nitric oxide

You may not qualify if…

• Serious congenital malformations or chromosomal abnormalities
• Life expectancy <7 days from enrollment
• Clinically unstable
• Less tha 48 hours since last dose surfactant
• Ability to obtain 36 week primary outcome information is unlikely

Where it is running

• University of Arkansas - Arkansas Childrens Hospital — Little Rock, Arkansas, United States
• Alta Bates Medical Center — Berkeley, California, United States
• Oakland Children's Hospital — Oakland, California, United States
• University of California, San Francisco — San Francisco, California, United States
• Wolfson Children's Hospital and Shands HospitaL — Jacksonville, Florida, United States
• Florida Hospital for Children — Orlando, Florida, United States
• All Children's Hospital — St. Petersburg, Florida, United States
• Northwestern Memorial Hospital — Chicago, Illinois, United States
• Children's Memorial Hospital — Chicago, Illinois, United States
• Childrens Hospital and Clinics of Minnesota- Minneapolis — Minneapolis, Minnesota, United States
• University of Minnesota Medical School — Minneapolis, Minnesota, United States
• Children's Hospital and Clinics of Minnesota - St Paul — Saint Paul, Minnesota, United States
• Children's Mercy Hospital — Kansas City, Missouri, United States
• Women's and Children's Hospital of Buffalo — Buffalo, New York, United States
• Stony Brook University Medical Center — Stony Brook, New York, United States
• Wake Forest University- Forsyth Hospital and Brenner Hospital — Winston-Salem, North Carolina, United States
• Medical University of South Carolina(MUSC) — Charleston, South Carolina, United States
• UT Memphis- Memphis Medical Center — Memphis, Tennessee, United States
• UT Houston Health Science Center — Houston, Texas, United States
• Texas Children's Hospital — Houston, Texas, United States
• University of Washington, Seattle — Seattle, Washington, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.