Quantitative Automated Lesion Detection of Traumatic Brain Injury

Completed

Conditions studied: Traumatic Brain Injury

In brief

The investigators propose to develop quantitative automated lesion detection (QALD) procedures to identify brain damage following traumatic brain injury more accurately than is possible with a normal magnetic resonance imaging (MRI) scans. These procedures require about 1 hour of imaging in an MRI scanner. Subjects will also undergo about 2 hours of cognitive tests. The investigators will compare the results of the cognitive tests with those from MRI scanning to determine what brain regions are responsible for superior performance and for performance decrements.

Key facts

Study ID

NCT01022307

Run by

VA Office of Research and Development

People needed

212

Starts

2009-05-01

Expected to finish

2014-10-01

Last updated by the study team

2016-01-14

Who can join

Age: 18 and older, up to 50. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Control subjects from 18-50.
• Patients from 18-50 who have suffered TBI.

You may not qualify if…

• Substance abuse.
• Irremedial sensory deficits (blindness, deafness).
• Primary psychiatric disorder.
• Neurological disease unrelated to TBI.

Where it is running

• VA Northern California HCS — Martinez, California, United States

Full record on ClinicalTrials.gov

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