Evaluate a Medication on How Hunger and Appetite Are Influenced by Smell

Stopped early · Phase 1 · Has a placebo group

Conditions studied: Food Intake

In brief

The purpose of this study is to determine whether the blood pressure medication, diltiazem, will temporarily decrease the sense of smell when given in a nasal spray which will then reduce food intake.

Key facts

Study ID

NCT01021176

Run by

Pennington Biomedical Research Center

People needed

12

Starts

2009-10-01

Expected to finish

2009-11-01

Last updated by the study team

2015-12-18

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Body mass index (BMI) between 25 and 40 kg
• Blood pressure in within normal range

You may not qualify if…

• Used tobacco products in the past month
• Used a calcium channel blocker medication in the last month
• used nasal sprays in the last month
• have an abnormal sense of smell or abnormalities of the lining in your nose
• female and have irregular menstrual periods
• female and are nursing a baby or pregnant
• female and have had a partial hysterectomy (still have ovaries)

Where it is running

• Pennington Biomedical Research Center — Baton Rouge, Louisiana, United States

Full record on ClinicalTrials.gov

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