AZD7268 Safety and Tolerability Study

Completed · Phase 2 · Has a placebo group

Conditions studied: Major Depressive Disorder

In brief

The purpose of this study is to prove the principle that treatment with AZD7268 reduces depressive symptoms in patients with Major Depressive Disorder (MDD) compared with placebo.

Key facts

Study ID

NCT01020799

Run by

AstraZeneca

People needed

247

Starts

2009-11-01

Expected to finish

2010-04-01

Last updated by the study team

2012-04-17

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Provision of signed, written, and dated Informed Consent prior to any study specific procedures
• Documented primary clinical diagnosis meeting criteria from the DSM-IV, Text Revision (APA 2000) for any of the following:
• 296.2x Major Depressive Disorder, Single Episode, or
• 296.3x Major Depressive Disorder, Recurrent

You may not qualify if…

• Patients with a secondary DSM-IV Axis I disorder other than GAD or social anxiety disorder (as assessed by MINI), provided the primary diagnosis is MDD. This diagnosis should have been made at least 6 months before enrollment
• Patients with a diagnosis of DSM-IV Axis II disorder which has a major impact on the patient's current psychiatric status
• Patients whose current episode of depression started less than 4 weeks before enrollment

Where it is running

• Research Site — Birmingham, Alabama, United States
• Research Site — Garden Grove, California, United States
• Research Site — San Diego, California, United States
• Research Site — New Haven, Connecticut, United States
• Research Site — Bradenton, Florida, United States
• Research Site — Jacksonville, Florida, United States
• Research Site — Atlanta, Georgia, United States
• Research Site — Rockville, Maryland, United States
• Research Site — Cedarhurst, New York, United States
• Research Site — New York, New York, United States
• Research Site — Rochester, New York, United States
• Research Site — Dayton, Ohio, United States
• Research Site — Portland, Oregon, United States
• Research Site — Memphis, Tennessee, United States
• Research Site — Friendswood, Texas, United States
• Research Site — Bellevue, Washington, United States
• Research Site — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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