Riluzole and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

Stopped early · Phase 1

Conditions studied: Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific

In brief

RATIONALE: Radiation therapy uses high energy x-rays to kill tumor cells. Drugs, such as riluzole, may make tumor cells more sensitive to radiation therapy. Giving riluzole together with whole-brain radiation therapy may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of riluzole when given together with whole-brain radiation therapy in treating patients with brain metastases.

Key facts

Study ID

NCT01018836

Run by

Rutgers, The State University of New Jersey

People needed

9

Starts

2009-11-01

Expected to finish

2013-12-01

Last updated by the study team

2014-05-02

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School — New Brunswick, New Jersey, United States

Full record on ClinicalTrials.gov

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