Genetic Mechanisms in Human Hypertension Renin-angiotensin-aldosterone System (RAAS) Inhibition Study

Withdrawn before enrolling · Not applicable

Conditions studied: Hypertension

In brief

The purpose of this study is to develop an approach to provide personalized medicine to individuals who have hypertension (high blood pressure). The investigators plan to use people's genetic characteristics (traits) to determine what medication they should use to lower their blood pressure most effectively. The investigators will give individuals one of two medications to treat hypertension (lisinopril or atenolol). The investigators believe that depending on the individuals genetic background one medication will work better in lowering their blood pressure.

Key facts

Study ID

NCT01009944

Run by

Brigham and Women's Hospital

People needed

0

Starts

2007-01-01

Expected to finish

2019-03-19

Last updated by the study team

2021-04-09

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male and female hypertensive participants who were previously studied in SCOR program.

You may not qualify if…

• Diabetes
• Taking other medications beside thyroid or estrogen supplements.

Where it is running

• Brigham and Women's Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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