Measured Hypocretin Levels and Recovery After Hip Surgery
Status unconfirmed
Conditions studied: Osteoarthritis, Hip
In brief
A specific group of neurons in the brain produces hypocretin, a peptide which has been established as an important regulator of sleep and wakefulness. Activation of these neurons (increased hypocretin) stabilizes wakefulness; impairing or blocking these neurons (decreased hypocretin) promotes sleep. Evidence suggests that these neurons may be involved in the hypnotic properties of several anesthetics, and play a role in the induction and emergence from anesthesia. In humans there is a considerable inter-individual variability in hypocretin levels. This study aims to investigate how hypocretin levels affect the anesthetic care and recovery of patients undergoing elective hip surgery.
Key facts
- Study ID
- NCT01009710
- Run by
- Stanford University
- People needed
- 50
- Starts
- 2009-07-01
- Expected to finish
- 2018-12-01
- Last updated by the study team
- 2017-01-18
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Stanford University School of Medicine — Stanford, California, United States
Full record on ClinicalTrials.gov
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