Clearance of Nasal Staphylococcus Aureus With Triple Antibiotic Ointment

Completed · Not applicable

Conditions studied: Nasal Carriers of Staphylococcus Aureus

In brief

Staphylococcus aureus, a bacteria that lives commonly in the anterior nostrils, is seen in about 30% of healthcare workers. Applying mupirocin ointment, a prescription, to the nostrils twice daily for 5 days is the current standard of care for treatment to clear this bacteria. This research study is designed to determine the rate of clearance of this bacteria in healthcare workers who are carriers when using triple antibiotic ointment instead of mupirocin ointment.

Key facts

Study ID

NCT00997139

Run by

Northwestern University

People needed

216

Starts

2009-09-01

Expected to finish

2010-11-01

Last updated by the study team

2015-01-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Willing and able to give informed consent
• Must have consented prior to registration for the study

You may not qualify if…

• active infection
• concurrent treatment with antibiotics, topical or systemic
• S. aureus decolonization attempt in prior six months
• history of HIV
• chemotherapy or systemic immunosuppressive therapy
• history of neomycin allergy or sensitivity

Where it is running

• Northwestern University — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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