Study of Tranilast Alone or in Combination With Febuxostat in Patients With Hyperuricemia

Completed · Phase 2

Conditions studied: Gout, Hyperuricemia

In brief

This is a randomized, double-blind, 3-period crossover phase 2 study in patients with documented hyperuricemia to evaluate the effect of tranilast on febuxostat pharmacokinetics (PK) and pharmacodynamics (PD) and to evaluate the effect of febuxostat on tranilast PK and PD as measured by reduction in serum uric acid levels.

Key facts

Study ID

NCT00995618

Run by

Nuon Therapeutics, Inc.

People needed

24

Starts

2009-09-01

Expected to finish

2010-04-01

Last updated by the study team

2011-01-06

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female, aged 18 to 70
• Subjects with hyperuricemia who are otherwise healthy

You may not qualify if…

• Pregnant or nursing
• Known history of gout
• Clinically significant infection at Screening
• Known sensitivity to tranilast or febuxostat

Where it is running

• Nuon Investigative Site — Honolulu, Hawaii, United States
• Nuon Investigative Site — Evansville, Indiana, United States
• Nuon Investigative Site — Dallas, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.