Is Pleth Variability Index (PVI) a Surrogate for Pulse Pressure Variations (PPV) in Pediatric Spine Fusion (SF) Surgery?

Completed

Conditions studied: Scoliosis, Spinal Fusion

In brief

Spine fusion is an involved procedure during which patients are at risk for significant intra-operative blood loss.This study will compare 2 ways of determining fluid status and response to fluid administration. One way is to measure the changes in the arterial wave form from the special IV that is usually placed in an artery (PPV). The second way is to use a non-invasive method of a finger probe that measures changes in the plethysmogram or the pleth variability index (PVI). No actual patient treatments will be based on these values during surgery.

Key facts

Study ID

NCT00994656

Run by

Children's Hospital of Philadelphia

People needed

24

Starts

2009-10-01

Expected to finish

2010-07-01

Last updated by the study team

2011-02-11

Who can join

Age: 8 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Males or females age 8 to 18 years inclusive.
• History of idiopathic or neuromuscular scoliosis.
• Scheduled for posterior spinal fusion.
• Parental/guardian permission (informed consent) and if appropriate, child assent.

You may not qualify if…

• Inability to understand or read English to provide consent.

Where it is running

• The Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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