A Study of MM-121 Combination Therapy in Patients With Advanced Non-Small Cell Lung Cancer

Completed · Phase 1/Phase 2

Conditions studied: Carcinoma, Non-Small-Cell Lung

In brief

A Phase 1-2 study of MM-121 in combination with standard therapy for non-small cell lung cancer (NSCLC).

Key facts

Study ID

NCT00994123

Run by

Merrimack Pharmaceuticals

People needed

162

Starts

2010-02-01

Expected to finish

2015-06-01

Last updated by the study team

2016-08-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with locally advanced or metastatic non-small cell lung cancer.
• Patients must be >/= 18 years of age.
• Patients must have adequate Performance Status (PS) as measured by ECOG and adequate end organ function.

You may not qualify if…

• Patients with a recent history (within 5 years) of another malignancy.
• Patients who are pregnant or nursing.
• Patients with clinically significant heart failure.
• Patients with clinically significant eye or gastrointestinal abnormalities.

Where it is running

• Study site — Birmingham, Alabama, United States
• Study site — Tucson, Arizona, United States
• Study site — Loma Linda, California, United States
• Study site — Sacramento, California, United States
• Study site — San Francisco, California, United States
• Study site — Aurora, Colorado, United States
• Study site — Tampa, Florida, United States
• Study site — Atlanta, Georgia, United States
• Study site — Lafayette, Indiana, United States
• Study site — Boston, Massachusetts, United States
• Study site — St Louis, Missouri, United States
• Study site — Buffalo, New York, United States
• Study site — New York, New York, United States
• Study site — Cincinnati, Ohio, United States
• Study site — Portland, Oregon, United States
• Study site — Pittsburgh, Pennsylvania, United States
• Study site — Charleston, South Carolina, United States
• Study site — Nashville, Tennessee, United States
• Study site — Dallas, Texas, United States
• Study site — Edmonton, Alberta, Canada
• Study site — Toronto, Ontario, Canada
• Study site — Montreal, Quebec, Canada
• Study site — Heidelberg, Mannheim, Germany
• Study site — Bad Berka, Germany
• Study site — Frankfurt, Germany

Full record on ClinicalTrials.gov

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