Deep Brain Stimulation (DBS) Frequency Effects on Gait in Parkinson's Disease(PD)

Completed · Phase 1/Phase 2

Conditions studied: Parkinson Disease

In brief

In this study the investigators will evaluate the effect of both low and high frequency Deep Brain stimulation of the subthalamic nucleus (STN) in Parkinson's patients who have noted a change in their walking. The investigators' hypothesis is: 1. Stimulation at 60 Hertz (Hz) is associated with improved gait with increased stride length and faster time on the Stand walk sit test. 2. There is no worsening of the Unified Parkinson's Disease Rating Scale (UPDRS) at 60 Hz.

Key facts

Study ID

NCT00993291

Run by

Vanderbilt University

People needed

20

Starts

2009-11-01

Expected to finish

2011-08-01

Last updated by the study team

2012-01-27

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Be a patient at the Vanderbilt Movement Disorders clinic.
• Report a change in their gait.
• Be able to walk independently when off PD medications for 12-16 hours.
• Have a stable dose of PD medications for the prior three months .
• Not cognitively impaired, so as to give informed consent.
• MMSE > 24.

You may not qualify if…

• See inclusion criteria.

Where it is running

• Vanderbilt University — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

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