Energy Expenditure Responses to Acute Exercise in Older Women (Calorie Expenditure and Exercise)
Completed · Not applicable
Conditions studied: Aging
In brief
In older, normal-weight women (60-75 yrs, BMI=18-28 kg/m2), an acute bout of higher-intensity (60% of maximum effort) aerobic exercise, in comparison to an isocaloric bout of lower-intensity (45% of maximum effort) exercise (caloric expenditure of 3.5 kcal/kg body weight for both), will result in differential: 1. decline in non-exercise activity calorie expenditure in the subsequent 48 hours after exercise; 2. increase in resting metabolic rate 48 hours after exercise; 3. increase in serum free triiodo-L-thyronine (free T3) concentrations immediately following exercise; 4. decline from pre-exercise in plasma leptin and serum free T3 concentrations 48 hours after exercise.
Key facts
- Study ID
- NCT00988299
- Run by
- Washington University School of Medicine
- People needed
- 26
- Starts
- 2009-10-01
- Expected to finish
- 2011-12-01
- Last updated by the study team
- 2011-12-06
Who can join
Age: 60 and older, up to 75. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- Women
- Age 60-75 years
- normal weight
- Weight-stable (± 5%) within the previous 3 months
- Non-smoking for last year
- Able to provide own transportation to study visits
- Not currently involved in any other research study
- Willing and able to participate in all aspects of the trial including research testing
- Willing to give informed consent to participate
You may not qualify if…
- Self-reported significant cardiovascular disease
- Other self-reported medical conditions such as diabetes, chronic or recurrent respiratory conditions, active cancer, musculoskeletal disease
- Medications known to affect exercise performance or metabolism
- Excess caffeine use (> 500mg/day)
- Any self-reported contraindications to exercise
- Clinical depression
- Abnormal cognitive function -
Where it is running
- Washington University School of Medicine — St Louis, Missouri, United States
Full record on ClinicalTrials.gov
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