The Effects AZD8529 on Ketamine-induced Impairment of Working Memory in Healthy Volunteers

Completed · Early Phase 1 · Has a placebo group

Conditions studied: Healthy, Memory Impairment

In brief

The purpose of this study is to assess if ketamine will induce, in healthy volunteers, impairment of working memory and if the drug AZD8529 will block the effects of ketamine on working memory as assessed by functional magnetic resonance imaging (fMRI).

Key facts

Study ID

NCT00985933

Run by

AstraZeneca

People needed

20

Starts

2010-02-01

Expected to finish

2011-04-01

Last updated by the study team

2011-05-04

Who can join

Age: 21 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Right handed
• 12th grade education or equivalent
• Able to read and write English as primary language

You may not qualify if…

• History of head injury
• Substance abuse or dependence
• History of claustrophobia

Where it is running

• Research Site — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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