The INFUSE - Anterior Myocardial Infarction (AMI) Study
Completed · Not applicable
Conditions studied: Acute Anterior Myocardial Infarction
In brief
This is a multicenter, open-label, controlled, single-blind, randomized study with up to 452 subjects enrolled in up to 50 US and European sites. Subjects who present with anterior ST-elevation myocardial infarction (STEMI) and an occluded proximal or mid left anterior descending (LAD) with TIMI 0/1/2 flow will be eligible for randomization to one of the following arms: 1. Local infusion of abciximab following thrombus aspiration 2. Local infusion of abciximab and no thrombus aspiration 3. No local infusion and thrombus aspiration 4. No local infusion and no thrombus aspiration In addition, a cardiac magnetic resonance imaging (MRI) sub-study evaluating microvascular obstruction (MVO) will be performed with up to 160 subjects at up to 20 sites.
Key facts
- Study ID
- NCT00976521
- Run by
- Atrium Medical Corporation
- People needed
- 452
- Starts
- 2009-09-01
- Expected to finish
- 2013-04-01
- Last updated by the study team
- 2013-07-08
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Washington Adventist Hospital — Takoma Park, Maryland, United States
- Carolinas Medical Center-SHVI — Charlotte, North Carolina, United States
- Moses Cone Vascular Center — Greensboro, North Carolina, United States
- Geisinger Medical Center — Danville, Pennsylvania, United States
- Harrisburg Hospital/ Pinnacle Health — Harrisburg, Pennsylvania, United States
- Wellmont Holston Valley Medical Center — Kingsport, Tennessee, United States
- Sentara Virginia Beach General Hospital — Virginia Beach, Virginia, United States
- Landeskrankenhaus Bruck/Mur — Bruck/Mur, Austria, Austria
- Landeskrankenhaus Graz West — Graz, Austria, Austria
- Univ. Klinik für Innere Medizin III Innsbruck — Innsbruck, Austria, Austria
- Univ. Klinik für Innere Medizin II — Vienna, Austria, Austria
- Landeskrankenhaus Braunau/Simbach — Braunau am Inn, Austria
- Universitätsmedizin Mannheim - I. Medizinische Klinik — Mannheim, Germany, Germany
- Klinikum der Universität Regensburg — Regensburg, Germany, Germany
- Charite- University Medicine Campus Benjamin Franklin — Berlin, Germany
- Klinikum Villingen Kardiologie — Darmstadt, Germany
- Facharzt fur Innere Medizin/Kardiologie — Ludwigshafen, Germany
- Universtitätsklinikuim Ulm — Ulm, Germany
- Ziekenhuis Rijnstate — Arnhem, NL, Netherlands
- Catharina Hospital Eindhoven — Eindhoven, Netherlands
- Isala Klinieken, Locatie de Weezenlanden — Zwolle, Netherlands
- Polsko - Amerykańskie Kliniki Serca II Oddział Kardiologiczny American Heart of Poland Sp. z o.o. — Bielsko-Biala, Poland, Poland
- Krakowski Szpital Specjalistyczny im. Jana Pawła II w Krakowie, Centrum Interwencyjne Leczenia Chorób Serca i Naczyń — Krakow, Poland, Poland
- SPZOZ Szpital Uniwersytecki w Krakowie, Samodzielna Pracownia Hemodynamiki i Angiografii — Krakow, Poland, Poland
- Samodzielny Publiczny Centralny Szpital Kliniczny w Warszawie Pracownia Hemodynamiki I Katedry i Kliniki Kardiologii — Warsaw, Poland, Poland
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.