Gabapentin Treatment of Cannabis Dependence

Completed · Phase 2 · Has a placebo group

Conditions studied: Cannabis Dependence, Cannabis Withdrawal, Cognitive Deficits

In brief

This is a clinical study to evaluate the efficacy of the medication gabapentin in treating persons with cannabis dependence.

Key facts

Study ID

NCT00974376

Run by

The Scripps Research Institute

People needed

150

Starts

2009-11-04

Expected to finish

2016-05-19

Last updated by the study team

2017-06-06

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Males or females from 18-65 years of age
• Meets DSM IV criteria for current cannabis dependence
• Seeking research-based outpatient treatment for cannabis dependence that involves daily medication
• Smoked MJ daily at least 25 days per month during the 90 days prior to randomization
• At least a 2-year history of regular MJ use

You may not qualify if…

• Abstinent from cannabis more than 2 days at the time of randomization
• Active suicidal ideation
• Currently meets DSM IV criteria for abuse or dependence on other substances, or has urine drug screen positive for substances, other than cannabis or nicotine
• Significant medical disorders that will increase potential risk or interfere with study participation,
• Sexually active female participants with childbearing potential who are pregnant, nursing or refuse to use a reliable method of birth control
• Meets DSM IV criteria for a major AXIS I disorder other than cannabis and nicotine dependence,
• Inability to understand and/or comply with the provisions of the protocol and consent form
• Treatment with an investigational drug during the previous month
• Sensitivity to study drug as evidenced by adverse drug experiences with gabapentin or its ingredients
• Ongoing treatment with medications that may affect study outcomes

Where it is running

• The Scripps Research Institute — La Jolla, California, United States

Full record on ClinicalTrials.gov

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