Thyroid Function in Late Preterm Infants

Completed

Conditions studied: Transient Hypothyroxinemia

In brief

Transient hypothyroxinemia (TH) is a condition characterized by low levels of serum thyroxine (T4) and normal levels of thyroid stimulating hormone (TSH). TH in premature infants has been found to be related to severity of illness. T4 levels in very low birth weight infants born prematurely has been found to be inversely correlated to severity of illness. In very low birth weight infants, TH has been associated with poor outcomes. Little is known about thyroid function in late preterm infants. Hypotheses: 1. Ill late preterm infants will have lower total T4 levels than healthy late preterm infants. 2. Total T4 and possibly TSH levels will be inversely correlated with short-term outcomes. 3. Late Preterm infants born by cesarean section will have lower T4 levels compared to those born by vaginal birth.

Key facts

Study ID

NCT00971555

Run by

Christiana Care Health Services

People needed

150

Starts

2009-09-01

Expected to finish

2011-01-01

Last updated by the study team

2011-03-23

Who can join

Age: any, up to 0. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• any infant born between 34 0/7 weeks and 36 6/7 weeks gestation born at Christiana Hospital

You may not qualify if…

• outborn infants
• infants with major congenital anomalies

Where it is running

• Christiana Hospital — Newark, Delaware, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.