Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy

Recruiting now · Not applicable

Conditions studied: Prostate Cancer

In brief

The purpose of this study is to see what effects, good and/or bad, proton radiation, and/or conventional radiation and hormonal therapy (if applicable), has on prostate cancer that has already returned or the risk of prostate cancer returning.

Key facts

Study ID

NCT00969111

Run by

Proton Collaborative Group

People needed

70

Starts

2009-08-01

Expected to finish

2050-08-01

Last updated by the study team

2026-06-17

Who can join

Age: 18 and older. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Prostate cancer treated primarily with open, laparoscopic or robotically assisted prostatectomy.
• Maximum PSA value of 20 ng/ml.

You may not qualify if…

• Evidence of distant metastasis (M1).
• Prior systemic chemotherapy for any reason.
• Previous irradiation to the pelvis that would compromise the ability to deliver the prescribed study treatment.
• Active inflammatory bowel disease (Crohn's disease, diverticulitis or ulcerative colitis) affecting the rectum. (Non-active diverticulitis and Crohn's disease not affecting the rectum are allowed).
• Prior or concurrent cancer, other than non-melanomatous skin cancer, unless disease free for at least 5 years.
• Taking Saw Palmetto or methotrexate and unable or unwilling to discontinue its use during radiation.

Where it is running

• Proton Center of Arkansas — Little Rock, Arkansas, United States (enrolling)
• University of Florida Proton Therapy Institute — Jacksonville, Florida, United States (enrolling)
• Northwestern Medicine Chicago Proton Center — Warrenville, Illinois, United States (enrolling)
• McLaren Proton Therapy Center — Flint, Michigan, United States (enrolling)
• Mercy David C. Pratt Cancer Center — St Louis, Missouri, United States (enrolling)
• Inova Schar Cancer Institute — Fairfax, Virginia, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.