Escitalopram (Lexapro) for Depression MS or ALS

Completed · Phase 3

Conditions studied: Major Depression, Multiple Sclerosis, Amyotrophic Lateral Sclerosis

In brief

The purpose of this study is to see if escitalopram (Lexapro) improves symptoms of major depressive disorder in patients who have ALS or MS.

Key facts

Study ID

NCT00965497

Run by

University of South Carolina

People needed

13

Starts

2009-07-01

Expected to finish

2010-03-01

Last updated by the study team

2019-05-01

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients between 18 and 70 years of age with documented ALS or MS,
• DSM-IV episode of non-psychotic Major Depression,
• ≥14 score on the 17-item HAM-D,
• Ability to give informed consent.

You may not qualify if…

• History of psychotic disorders,
• Psychotic depression,
• Bipolar depression,
• Suicide risk,
• History of substance abuse in the previous 6 months,
• History of unstable medical disorders,
• Pregnancy or planning for pregnancy,
• Severity of ALS or MS that limits participating in the study protocol.

Where it is running

• University of South Carolina School of Medicine — Columbia, South Carolina, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.