The Effects of Sildenafil on Exercise Function and Capacity in Patients With Fontan Circulation

Completed · Phase 4 · Has a placebo group

Conditions studied: Fontan Circulation

In brief

The study will test the hypothesis that a single dose of sildenafil can increase the exercise capacity of pediatric patients with a Fontan Circulation.

Key facts

Study ID

NCT00964782

Run by

Milton S. Hershey Medical Center

People needed

17

Starts

2009-08-01

Expected to finish

2012-05-24

Last updated by the study team

2019-03-26

Who can join

Age: 6 and older, up to 17. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 6-17 years
• Male or female
• Possess Fontan Circulation

You may not qualify if…

• Severe heart failure (New York Heart Ass. functional class IV)
• Evidence of Fontan pathway obstruction
• History of exercise-induced severe arrhythmias
• Pregnancy (known or suspected)
• Orthopedic limitations that prevent ambulation on a treadmill
• Use of nitroglycerin
• Herbal medications

Where it is running

• Penn State Hershey Medical Center — Hershey, Pennsylvania, United States

Full record on ClinicalTrials.gov

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