Assessment of Outcome of Meniscus Repair With or Without Platelet Rich Plasma

Withdrawn before enrolling · Not applicable

Conditions studied: Cartilage Disease

In brief

The purpose of this investigation is to determine the clinical outcome of repair of meniscus tears located in the "red/white" region using a well-known suture technique combined, when indicated, with platelet-rich plasma to enhance healing. The outcome of this operation will be determined in a consecutive group of patients with an established, rigorous knee rating system a minimum of 2 years postoperatively. Results will be determined by the analysis of subjective and functional factors, sports and occupational activity levels, a comprehensive physical examination, and a radiographic evaluation using standard plain x-rays and magnetic resonance imaging. The investigators hypothesize that meniscus repairs will significantly reduce tibiofemoral compartment pain and allow for increased knee function and activity levels. The platelet rich plasma adjunct will be used in complex meniscus tears in which a portion of the tear extends into the avascular region classified as either longitudinal, horizontal, or radial. The investigators hypothesize that the healing rate of these repairs will be superior to those previously reported in clinical studies in patients who had the suture repair technique alone.

Key facts

Study ID

NCT00961597

Run by

Sue Barber-Westin

People needed

0

Starts

2009-09-01

Expected to finish

2014-12-01

Last updated by the study team

2014-12-11

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients scheduled for meniscus repair who provide informed consent to participate

You may not qualify if…

• Patients scheduled for meniscus repair who refuse to participate
• Presence of a tumor, metastatic disease, active infections, platelet count < 10 5/hl Hgb < 10 g/dl, pregnancy, active breastfeeding, and allergy to Bupivicaine
• Patients with preexisting thrombocytopenia, hypofibrinogenemia, or who are on anti-coagulant therapy, or who have a potential hypersensitivity to bovine products

Where it is running

• Cincinnati Sportsmedicine and Orthopaedic Center — Cincinnati, Ohio, United States

Full record on ClinicalTrials.gov

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