Topical Budesonide Treatment for Eosinophilic Esophagitis (EoE)

Completed · Not applicable

Conditions studied: Eosinophilic Esophagitis

In brief

The purpose of this study is to conduct a clinical trial of two formulations of budesonide (nebulized/swallowed versus viscous/swallowed) in patients with EoE to determine if medication contact time and distribution in the esophagus relates to treatment response. The investigators will also determine if there is systemic absorption of these topical steroids. The investigators hypothesize that tissue and symptom response will correlate with esophageal medication contact time and distribution, and that significant systemic absorption will not be seen.

Key facts

Study ID

NCT00961233

Run by

University of North Carolina, Chapel Hill

People needed

25

Starts

2009-10-01

Expected to finish

2011-11-01

Last updated by the study team

2012-11-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• New diagnosis of eosinophilic esophagitis (per 2007 consensus guidelines)

You may not qualify if…

• Age < 18
• Inability to read or understand English
• Pregnant or nursing women
• Previous allergic reactions to steroid medications
• Current use of systemic steroids

Where it is running

• University of North Carolina — Chapel Hill, North Carolina, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.