A Long Term Extension Study Evaluating ACC-001 With QS-21 in Subjects With Mild to Moderate Alzheimer's Disease

Stopped early · Phase 2

Conditions studied: Alzheimer Disease

In brief

The purpose of this study is to assess the long term safety, tolerability, and immunogenicity of ACC-001, an investigational vaccine, plus QS-21 in subjects with mild to moderate Alzheimer's disease.

Key facts

Study ID

NCT00960531

Run by

Pfizer

People needed

160

Starts

2009-07-01

Expected to finish

2013-12-01

Last updated by the study team

2016-04-01

Who can join

Age: 50 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects randomized under previous 3134K1-2201 study (NCT00498602) and met all inclusion/and none of the exclusion criteria.
• Screening brain MRI scan is consistent with the diagnosis of AD.
• Mini-Mental State Examination (MMSE) score greater than or equal to 10.
• Other criteria apply.

You may not qualify if…

• Significant Neurological Disease other than Alzheimer's disease.
• Current clinically significant systemic illness.
• Other exclusion criteria apply.

Where it is running

• Banner Alzheimer's Institute — Phoenix, Arizona, United States
• Banner Boswell Medical Center — Sun City, Arizona, United States
• Banner Sun Health Research Institute — Sun City, Arizona, United States
• University of California San Francisco — San Francisco, California, United States
• University of California, San Francisco — San Francisco, California, United States
• University of California - San Francisco — San Francisco, California, United States
• University of California San Francisco — San Francisco, California, United States
• University of California, San Francisco — San Francisco, California, United States
• Yale New Haven Hospital — New Haven, Connecticut, United States
• Yale University School of Medicine — New Haven, Connecticut, United States
• Yale-New Haven Hospital — New Haven, Connecticut, United States
• General Clinical Research Unit — Washington D.C., District of Columbia, United States
• Georgetown University Medical Center — Washington D.C., District of Columbia, United States
• MD Clinical — Hallandale, Florida, United States
• Palm Beach Neurology - Premiere Research Institute — West Palm Beach, Florida, United States
• Brigham and Woman's Hospital — Boston, Massachusetts, United States
• Center for Alzheimer Research and Treatment — Boston, Massachusetts, United States
• Barnes Jewish Hospital — St Louis, Missouri, United States
• Washington University School of Medicine — St Louis, Missouri, United States
• Barnes Jewish Hospital at Washington University — St Louis, Missouri, United States
• Washington University School of Medicine — St Louis, Missouri, United States
• Memory Enhancement Center of America, Inc. — Eatontown, New Jersey, United States
• Columbia University/Taub Institute — New York, New York, United States
• CUMC Research Pharmacy — New York, New York, United States
• Butler Hospital — Providence, Rhode Island, United States

Full record on ClinicalTrials.gov

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