Smoking Cessation for Veterans With Severe and Persistent Mental Illness

Completed · Phase 2/Phase 3

Conditions studied: Schizoaffective Disorder, Schizophrenia, Affective Psychosis, Bipolar, Affective Disorders, Psychotic

In brief

The investigators have developed an intervention called Behavioral Treatment of Smoking Cessation in SPMI (BTSCS), an innovative intervention that supplements pharmacotherapy and education with contingency management and a multifaceted behavioral group treatment program that lasts for three months (24 group meetings). BTSCS is designed to address the cognitive, motivational, and social support problems characteristic of people with SPMI. The investigators propose to conduct a randomized trial for persons with SPMI that compares (1) BTSCS: a 6-month manualized smoking cessation program adapted from an effective substance abuse treatment program for this population to (2) StSST: a standard manualized smoking cessation program which reflects current best practices.

Key facts

Study ID

NCT00960375

Run by

US Department of Veterans Affairs

People needed

179

Starts

2010-04-01

Expected to finish

2014-12-01

Last updated by the study team

2015-08-18

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• DSM-IV diagnosis of severe and persistent mental illness (SPMI) including a diagnosis of a psychotic disorder in keeping with criteria established by the Serious Mental Illness Treatment Research and Evaluation Center (SMITREC) -Schizophrenic disorders, affective psychoses and other psychotic diagnoses. We also include individuals with a diagnosis of Major Depression with psychotic features and PTSD.
• Age 18-75
• Nicotine dependence as defined by a score of 5 or higher on the Fagerstrom Tolerance Scale OR Participants who currently smoke at least 10 cigarettes per day
• Participants will not meet criteria for current alcohol/substance dependence (other than nicotine)
• Willingness ability to provide consent to participate.

You may not qualify if…

• Documented history of severe neurological disorder or severe head trauma with loss of consciousness
• Severe or profound mental retardation by chart review.

Where it is running

• Washington DC VA Medical Center, Washington, DC — Washington D.C., District of Columbia, United States
• Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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