A Study of Vismodegib (GDC-0449) in Patients Treated With Vismodegib in a Previous Genentech-sponsored Phase I or II Cancer Study

Completed · Phase 2

Conditions studied: Ovarian Cancer, Basal Cell Carcinoma, Metastatic Colorectal Cancer

In brief

This was a multicenter, open-label extension study. Patients who received vismodegib (GDC-0449) in a Genentech-sponsored study and who had completed the parent study or who continued to receive vismodegib at the time the parent study closed were eligible for continued treatment in this protocol.

Key facts

Study ID

NCT00959647

Run by

Genentech, Inc.

People needed

19

Starts

2009-09-03

Expected to finish

2014-01-09

Last updated by the study team

2026-05-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Completed vismodegib treatment within 2-4 weeks in a Genentech-sponsored parent study or continued to receive vismodegib at the time the Genentech-sponsored parent study closed.
• Expectation by the investigator that the participant may continue to benefit from additional vismodegib treatment.

You may not qualify if…

• Intervening anti-tumor therapy not specified in the parent study (ie, non-protocol-specified chemotherapy, other targeted therapy, radiation therapy, or photodynamic therapy).

Where it is running

• TGen Clinical Research Srvs — Scottsdale, Arizona, United States
• Children's Hospital — Oakland, California, United States
• Comprehensive Cancer Care — Palm Springs, California, United States
• Stanford Univ Medical Center — Stanford, California, United States
• Johns Hopkins Univ Med Center — Baltimore, Maryland, United States
• University Of Michigan — Ann Arbor, Michigan, United States
• Karmanos Cancer Institute.. — Detroit, Michigan, United States
• Nevada Cancer Research Foundation — Las Vegas, Nevada, United States
• Irfan Firdaus, D.O. — Cincinnati, Ohio, United States
• DermSurgery Associates, PA — Houston, Texas, United States

Full record on ClinicalTrials.gov

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