Non-Invasive Non-Ionizing Polarized Imaging System to Assess Structure of Cervix
Stopped early
Conditions studied: Healthy
In brief
Background: * The uterine cervix is composed of muscle and collagen, which change as women age and under hormonal influences like puberty, pregnancy, and menopause. Yet even though knowledge of structure of the cervix (especially the collagen network) is important to detect problems that may affect pregnancy and other women s health issues, no noninvasive techniques are available to evaluate such changes. * A specially designed polarized camera attached to a conventional colposcope can be used to take cervical images. Analyzing these images may enable researchers to better visualize the collagen network in the cervix. Objectives: * To explore and gain experience with the use of a polarized imaging system to study cervical structure. * To evaluate the usefulness of a polarized imaging system in studying the cervical structure of healthy nonpregnant women. Eligibility: \- Adult females (at least 18 years of age) who are having regular menstrual cycles and are not on hormonal medications. Design: * Images will be takes from the cervix in two different phases of menstruation cycle time, one in the follicular phase (before ovulation) and another one in the luteal phase (after ovulation). * The images of the cervix will be taken with a vaginal speculum in place with the camera attached to a colposcope. The colposcope will illuminate the cervix using polarized light. Three random cervical locations will be photographed
Key facts
- Study ID
- NCT00955864
- Run by
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- People needed
- 12
- Starts
- 2009-07-15
- Expected to finish
- 2016-09-01
- Last updated by the study team
- 2017-10-06
Who can join
Age: 18 and older, up to 60. Sex: female. Healthy volunteers: not accepted.
You may not qualify if…
- Those with symptoms or signs of infection or are currently menstruating.
- Any medical condition that, in the opinion of Principal Investigator, would preclude the inclusion of a patient onto this research study.
- Unable or unwilling to give informed consent.
Where it is running
- National Institutes of Health Clinical Center, 9000 Rockville Pike — Bethesda, Maryland, United States
Full record on ClinicalTrials.gov
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