Effects of Antioxidants on Cardiovascular Risk Measures (Spice Study)

Completed · Not applicable · Has a placebo group

Conditions studied: Cardiovascular, Psychological Stress

In brief

The purpose of this study is to assess whether feeding highly antioxidant spices of providing these same antioxidants as capsules is able to affect cardiovascular risk measures. Because this is a new area of research, the investigators will use many measures to assess this question including blood markers, tests of blood vessel health, measures of blood pressure responses, measures of clotting activity, and other inflammation measures.

Key facts

Study ID: NCT00954902
Run by: Penn State University
People needed: 32
Starts: 2009-08-01
Expected to finish: 2010-09-01
Last updated by the study team: 2018-01-25

Who can join

Age: 30 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

Age 30-65
BMI 25-40
Non tobacco user
Resting BP < 160/100
Fasting Glucose < 126 mg/dL

You may not qualify if…

Tobacco use
Use of female hormones
Breastfeeding or planning to become pregnant during the study
Use of lipid-lowering or blood pressure medications
Chronic Inflammatory Disease or osteoarthritis requiring regular use of medication
Chronic use of any form of anti-inflammatory or anti-psychotic drugs
Use of daily aspirin or supplements (except stable dose of calcium)
History of heart attack or stroke, renal or hepatic disease, implanted medical devices, gastrointestinal disease
Allergy or intolerance to any study foods
Injury to fingers or arms that would interfere with vascular and blood pressure measurements
Inability to comply with study protocol
Allergy to adhesives or latex
Aerobic exercise exceeding 2 hours per week

Where it is running

Penn State GCRC — University Park, Pennsylvania, United States

Full record on ClinicalTrials.gov

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