Reduce Obesity and Diabetes
Status unconfirmed
Conditions studied: Type 2 Diabetes, Pediatric Obesity, Dyslipidemia
In brief
This study examines risk factors for type 2 diabetes in children representing multiple discrete ethnic groups. It also examines the short term effects of school-based health education supervised exercise on metabolic risk factors for type 2 diabetes mellitus in children. The investigators hypothesize that exercise and health education will significantly improve insulin sensitivity in all children, especially in children who are already insulin resistant, thereby lowering the risk that they will go on to develop type 2 diabetes mellitus. The specific hypotheses being tested are: 1. Insulin resistance will be most evident in overweight children while an impaired ability of the pancreas to release insulin will be most evident in children with a family history of type 2 diabetes mellitus. 2. Exercise will significantly improve insulin resistance (as measured by the fasting glucose/insulin ratio) with little effect on insulin secretory capacity in children. 3. Participation in a school-based health, nutrition, and exercise education program will have long term beneficial effects on health related behaviors and on insulin resistance in all children, regardless of their level of diabetes risk.
Key facts
- Study ID
- NCT00954577
- Run by
- Academy for Medical Development and Collaboration, New York
- People needed
- 1000
- Starts
- 2006-07-01
- Expected to finish
- 2012-06-01
- Last updated by the study team
- 2009-08-07
Who can join
Age: 10 and older, up to 15. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Children in 6th-8th grade
You may not qualify if…
- Diabetes
- Exercise induced asthma
- Pregnancy
- Any chronic medication that interferes with glucose homeostasis
Where it is running
- Maimonides Medical Center — Brooklyn, New York, United States (enrolling)
- North Shore LIJ Schneider Children's Hospital — Manhasset, New York, United States (enrolling)
- Winthrop University Hospital — Mineola, New York, United States (enrolling)
- Mt. Sinai Medical Center — New York, New York, United States (enrolling)
- Columbia University Medical Center/The New York Presbyterian Hospital — New York, New York, United States (enrolling)
Full record on ClinicalTrials.gov
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