Acute Cardiovascular and Metabolic Effects of Exercise Training in Individuals With Insulin Resistance

Completed · Not applicable

Conditions studied: Insulin Resistance

In brief

The overall aim of the project is to determine whether or not exercise influences cardiovascular or nervous responses to meal ingestion in individuals with insulin resistance or type 2 diabetes.

Key facts

Study ID

NCT00954109

Run by

US Department of Veterans Affairs

People needed

11

Starts

2009-08-01

Expected to finish

2010-12-01

Last updated by the study team

2015-04-06

Who can join

Age: 30 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Insulin resistant: diagnosed with pre-diabetes or fasting blood glucose >/= 100 mg/dL
• T2D: diagnosed by primary care physician
• BMI: less than 43 kg/m2
• Age: 30-65

You may not qualify if…

• Smoking
• Insulin use (other than once daily)
• Underlying conditions that limit ability to exercise safely
• Recent weight gain or loss (>5% of body weight in 3 months)
• Physically active (>30 min aerobic exercise, 2 d/wk)
• Recent (<3 mo) changes in medication use or dose
• Uncontrolled T2D (HbA1c>10%)
• Advanced retinopathy or neuropathy
• Pregnancy

Where it is running

• Harry S. Truman Memorial VA Medical Center — Columbia, Missouri, United States

Full record on ClinicalTrials.gov

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