Nicotine Patch, Blood Flow and Oxidative Stress Study

Completed · Not applicable · Has a placebo group

Conditions studied: Healthy

In brief

This study will address the hypothesis that nicotine, like cigarette smoking acting as a pro-oxidant may have adverse effects on arterial function.

Key facts

Study ID

NCT00954096

Run by

University of Pennsylvania

People needed

55

Starts

2002-10-01

Expected to finish

2006-12-01

Last updated by the study team

2009-10-27

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy individuals
• Nonsmokers who have never smoked
• Normal medical history
• Normal physical examination
• Normal laboratory data
• Negative urinary pregnancy test for females

You may not qualify if…

• Previous CVD
• Chronic medication use
• History alcoholism
• History of smoking
• Current pregnancy
• Subjects, who have less than or equal to 60% platelet aggregation in response to arachidonic acid will also be excluded.

Where it is running

• University of Pennsylvania — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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