Imaging of Brain Amyloid Plaques in the Aging Population

Enrolling by invitation · Phase 4

Conditions studied: Alzheimer's Disease, Dementia With Lewy Bodies, Frontotemporal Dementia, Vascular Dementia

In brief

This is a prospective, open label, non-therapeutic, diagnostic imaging study. The purpose of this study is to utilize Pittsburgh Compound B positron emission imaging (PiB PET) to ascertain the relationship between change in amyloid burden over time, and concurrent change in clinical status.

Key facts

Study ID

NCT00950430

Run by

Mayo Clinic

People needed

8000

Starts

2008-04-01

Expected to finish

2027-06-01

Last updated by the study team

2026-06-23

Who can join

Age: 30 and older, up to 100. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 30-100
• Subjects who have completed or are scheduled to undergo the neurological evaluation procedures in the Mayo Clinic Study of Aging, Mayo ADRC, or Mayo neurodegenerative disease clinics.

You may not qualify if…

• Subjects unable to lie down without moving for 10 minutes
• Women who are pregnant or cannot stop breast feeding for 24 hours at the time of scanning
• Claustrophobic patients unable to tolerate the scans
• Standard safety exclusionary criteria for MRI such as metallic foreign bodies, pacemaker, etc.

Where it is running

• Mayo Clinic — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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