Potassium Intake in Patients With Chronic Kidney Disease
Completed · Not applicable
Conditions studied: Chronic Kidney Disease, Hypertension
In brief
Chronic kidney disease is associated with high blood pressure, heart disease, and strokes. Potassium lowers blood pressure and may help prevent heart disease and strokes in the general population, but has not been well-studied in people with kidney disease. This study will look at the benefits and safety of two levels of potassium intake in patients with kidney disease. We expect that a higher level of potassium intake safely lowers blood pressure compared to a lower level of potassium intake. We hope that this and other research projects will help us to learn more so that guidelines can be created for potassium intake in patients with chronic kidney disease
Key facts
- Study ID
- NCT00949585
- Run by
- Johns Hopkins University
- People needed
- 29
- Starts
- 2009-07-01
- Expected to finish
- 2011-06-01
- Last updated by the study team
- 2012-09-19
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Stage 3 chronic kidney disease (estimated glomerular filtration rate 30-59 mL/min/1.73 m2 by the 4-variable Modification of Diet in Renal Disease (MDRD) Study Equation
- Systolic blood pressure 120-159 mm Hg and diastolic blood pressure < 100 mm Hg
- Willingness to follow strict dietary rules for 9 weeks and to come to the clinical research unit at least 3 weekdays per week for one meal during the two study periods
You may not qualify if…
- Baseline serum potassium of at least 5.5 mEq/L
- Baseline serum potassium of less than 3.5 mEq/L
- Insulin-requiring or uncontrolled (HbA1C > 9 g/dL) diabetes mellitus
- Use of potassium supplements
- Use of digoxin
- Chronic disease(s) that may interfere with trial participation
- Pregnancy or lactation
- > 14 alcoholic drinks/week
- Major food allergies or intolerances
Where it is running
- Johns Hopkins University Pro Health Clinical Research Facility — Baltimore, Maryland, United States
Full record on ClinicalTrials.gov
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