Effects of Chantix on Relapse Prevention for Smoking Cessation
Completed · Phase 4 · Has a placebo group
Conditions studied: Nicotine Dependence
In brief
The goal of the proposed study is to validate an experimental paradigm to assess medication effects on smoking relapse following a brief (3-day) monitored period of smoking abstinence and a programmed cigarette lapse.
Key facts
- Study ID
- NCT00948649
- Run by
- University of Pennsylvania
- People needed
- 62
- Starts
- 2006-09-01
- Expected to finish
- 2007-09-01
- Last updated by the study team
- 2010-08-17
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Eligible participants will be 68 (34 male and 34 female) smokers aged 18-65, who smoke ≥ 10 cigarettes per day, provide a baseline CO reading ≥ 10 ppm and who plan to live in the area for the next 6-months.
You may not qualify if…
- Smoking Behavior
- Use of chewing tobacco or snuff
- Current enrollment or plans to enroll in another smoking cessation program in the next 5 months
- Plan to use other nicotine substitutes or smoking cessation treatments in the next 5 months
- Provide a baseline CO reading < 10 ppm
- Alcohol/Drug Exclusion Criteria
- History of substance abuse and/or currently receiving treatment for substance abuse (e.g., alcohol, opioids, cocaine, marijuana, or stimulants)
- Current alcohol consumption that exceeds >25 standard drinks/week
- Medication Exclusion Criteria
- Current use or recent discontinuation (within last 14-days) of the following medications:
- Any form of smoking cessation medication (zyban, wellbutrin, wellbutrin SR, Chantix, NRT)
- Any form of anti-psychotic medications that includes:
- antipsychotics,
- atypical antipsychotics,
- mood-stabilizers,
- anti-depressants (tricyclics, SSRI's, MAOI's),
- anti-panic agents,
- anti-obsessive agents,
- anti-anxiety agents, and
- stimulants (e.g., Provigil, Ritalin).
- Medication for chronic pain
- Anti-coagulants
- Any heart medications
- Daily medication for asthma
- Medical Exclusion Criteria
Where it is running
- Tobacco Use Research Center, University of Pennsylvania — Philadelphia, Pennsylvania, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.