Development of a Biomarker Panel for the Earlier Prediction of Acute Kidney Injury in Patients With Diabetes
Recruiting now
Conditions studied: Diabetes Mellitus, Renal Impairment
In brief
Patients living with diabetes mellitus have double the risk of kidney failure compared to patients without diabetes following use of dye in many x-rays and procedures to diagnose and treat narrowing of the arteries (blood vessels) in the heart that can lead to angina or a heart attack. Heart disease is the commonest cause of death in patients with diabetes. People with diabetes are more likely to need these tests/treatments. By identifying those at greater risk of kidney complications we may be able to make these tests/treatments safer and offer them to more patients with diabetes.
Key facts
- Study ID
- NCT00948116
- Run by
- Barts & The London NHS Trust
- People needed
- 250
- Starts
- 2009-06-24
- Expected to finish
- 2025-12-31
- Last updated by the study team
- 2024-12-10
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age > 18 years, known diabetes mellitus or BM on arrival consistent with probable diagnosis of diabetes, eGFR <60 ml/min
- Undergoing a PCI procedure
- Agrees to the additional collection of blood and urine samples as outlined above
- Agrees to access of their clinical records for the collection of relevant medical data
- No history or signs of drug abuse
- Able to understand and sign the written Informed Consent Form
- Able and willing to follow the Protocol requirements
You may not qualify if…
- Cardiogenic shock
- Pregnancy
- Patient on renal replacement therapy (haemodialysis/CAPD/renal transplant)
- Known clinically significant infection such as HIV, Hepatitis or TB
- Any patient determined not able to make a reasoned, informed consent prior to the planned interventional procedure
Where it is running
- The London Chest Hospital — London, United Kingdom (enrolling)
Full record on ClinicalTrials.gov
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