S0910 Epratuzumab, Cytarabine, and Clofarabine in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia
Completed · Phase 2
Conditions studied: Leukemia
In brief
RATIONALE: Monoclonal antibodies, such as epratuzumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. Drugs used in chemotherapy, such as cytarabine and clofarabine, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving epratuzumab together with cytarabine and clofarabine may kill more cancer cells. PURPOSE: This phase II trial is studying the side effects and how well giving epratuzumab together with cytarabine and clofarabine works in treating patients with relapsed or refractory acute lymphoblastic leukemia.
Key facts
- Study ID
- NCT00945815
- Run by
- SWOG Cancer Research Network
- People needed
- 35
- Starts
- 2010-09-01
- Expected to finish
- 2017-08-01
- Last updated by the study team
- 2017-11-06
Who can join
Age: 16 and older, up to 120. Sex: any. Healthy volunteers: not accepted.
Where it is running
- City of Hope Comprehensive Cancer Center — Duarte, California, United States
- USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
- University of California Davis Cancer Center — Sacramento, California, United States
- Stanford Cancer Center — Stanford, California, United States
- University of Colorado Cancer Center at UC Health Sciences Center — Aurora, Colorado, United States
- St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center — Grand Junction, Colorado, United States
- H. Lee Moffitt Cancer Center and Research Institute at University of South Florida — Tampa, Florida, United States
- Cardinal Bernardin Cancer Center at Loyola University Medical Center — Maywood, Illinois, United States
- St. Francis Hospital and Health Centers - Beech Grove Campus — Beech Grove, Indiana, United States
- Reid Hospital & Health Care Services — Richmond, Indiana, United States
- Tulane Cancer Center Office of Clinical Research — Alexandria, Louisiana, United States
- Hematology-Oncology Clinic — Baton Rouge, Louisiana, United States
- University of Michigan Comprehensive Cancer Center — Ann Arbor, Michigan, United States
- University of Mississippi Cancer Clinic — Jackson, Mississippi, United States
- Saint Louis University Cancer Center — St Louis, Missouri, United States
- CCOP - Montana Cancer Consortium — Billings, Montana, United States
- St. Vincent Healthcare Cancer Care Services — Billings, Montana, United States
- Hematology-Oncology Centers of the Northern Rockies - Billings — Billings, Montana, United States
- Billings Clinic - Downtown — Billings, Montana, United States
- Bozeman Deaconess Cancer Center — Bozeman, Montana, United States
- Great Falls Clinic - Main Facility — Great Falls, Montana, United States
- Sletten Cancer Institute at Benefis Healthcare — Great Falls, Montana, United States
- St. Peter's Hospital — Helena, Montana, United States
- Glacier Oncology, PLLC — Kalispell, Montana, United States
- Arkansas Cancer Research Center at University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
Full record on ClinicalTrials.gov
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