Effect of Lactose, Fructose, Sucrose, Whey Protein, and Soy Protein on Substrate Absorption and Oxidation: a Pilot Study
Completed · Not applicable
Conditions studied: Substrate Absorption, Substrate Oxidation, Glucose Regulation
In brief
Does the consumption of various combinations of mono and disaccharides (lactose, sucrose and fructose) and protein isolates (whey or soy) result in altered substrate absorption, substrate oxidation, and glucose regulation? This proposed research will provide data to determine the relative contribution of source of protein (whey vs soy) and carbohydrate (mono- and disaccharides) on the observed effects of dairy products on absorption, substrate oxidation and glucoregulation mechanisms that affect body composition.
Key facts
- Study ID
- NCT00942513
- Run by
- United States Department of Agriculture (USDA)
- People needed
- 9
- Last updated by the study team
- 2011-02-09
Who can join
Age: 25 and older, up to 65. Sex: male. Healthy volunteers: accepted.
You may qualify if…
- Male.
- BMI at least 20 and less than 38 kg/m2 and body weight < 300 lbs.
- Age 25 to 65 years at beginning of study.
- Fasting glucose < 126 mg/dL.
- Blood pressure < 160/100 mm Hg.
- Total plasma cholesterol < 280 mg/dL.
- Nonsmokers or tobacco users (for at least 6 months prior to the start of the study.)
You may not qualify if…
- History or presence of kidney disease, liver disease, gout, certain cancers, thyroid disease, gastrointestinal, other metabolic diseases, or malabsorption syndromes.
- Type 2 diabetes requiring the use of oral antidiabetic agents or insulin.
- History of eating disorders.
- Volunteers who routinely participate in heavy exercise or volunteers who initiate an exercise program during the study.
- Volunteers who have lost 10% of body weight within the last 12 months .
- Volunteers who have been on Atkins, South Beach or similar diet in 3 months prior to start of study.
- Use of prescription or over-the-counter antiobesity medications or supplements (e.g., phenylpropanalamine, ephedrine, caffeine, during and for at least 6 months prior to the start of the study).
- Known (self-reported) allergy or adverse reaction to dairy products (including lactose) or soy.
- Volunteers who consume whey or soy protein supplements.
Where it is running
- USDA-ARS, Beltsville Human Nutrition Research Center — Beltsville, Maryland, United States
Full record on ClinicalTrials.gov
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