Naltrexone for At-Risk and Problem Drinking in Smoking Cessation Treatment
Completed · Phase 2 · Has a placebo group
Conditions studied: Hazardous Drinking, Cigarette Smoking
In brief
To test whether naltrexone compared to placebo can reduce heavy drinking and improve smoking cessation outcomes in heavy drinkers seeking smoking cessation treatment.
Key facts
- Study ID
- NCT00938886
- Run by
- Brown University
- People needed
- 150
- Starts
- 2009-10-01
- Expected to finish
- 2015-12-01
- Last updated by the study team
- 2017-05-15
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- 1.) be at least 18 years of age, 2.) drink heavily at least once per month on average (≥4 drinks per occasion for women; ≥5 drinks for men), 3.) have smoked cigarettes regularly for at least one year, 4.) currently smoke at least 5 cigarettes a day, 5.) currently be using no other tobacco products or nicotine replacement therapy
You may not qualify if…
- 1.) meet criteria for current substance dependence (excluding nicotine and alcohol); 2.) report opiate use in the past month, have a drug screen positive for opiates, or require opiate containing medications for pain management; 3.) meet criteria for a current major depressive or manic episode; 4.) are currently psychotic or suicidal; 5.) have an unstable or serious medical condition that would preclude use of the nicotine patch or naltrexone (e.g., unstable angina pectoris, severe arrhythmia, recent congestive heart failure); 6.) have aspartate aminotransferase or alanine aminotransferase levels of more than 3 times the reference range or elevated bilirubin levels; or 7.) are currently pregnant or lactating, intend to become pregnant, or are not using a reliable means of birth control.
Where it is running
- Brown University — Providence, Rhode Island, United States
Full record on ClinicalTrials.gov
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