Sleep Deprivation and Energy Balance

Completed · Not applicable

Conditions studied: Obesity

In brief

Observational and epidemiological studies have found a link between obesity and short sleep duration with the prevalence of both increasing in the past decades. At this time, it is unknown whether short sleep is a cause of obesity and how short sleep would lead to obesity. Some studies associate short sleep with increased levels of hormone that stimulate appetite. This study will examine how food intake and energy expenditure can be modified by sleep duration as a means of understanding a potential causal pathway.

Key facts

Study ID

NCT00935402

Run by

St. Luke's-Roosevelt Hospital Center

People needed

30

Starts

2008-11-01

Expected to finish

2010-07-01

Last updated by the study team

2011-02-23

Who can join

Age: 30 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Body mass index 22-25 kg/m2
• Right-handed
• Sleep 7-9 hours/night
• Normal score on Pittsburgh Quality of Sleep questionnaire, Epworth Sleepiness Scale, Berlin Questionnaire, Sleep Disorders Inventory Questionnaire, Beck Depression Inventory, Composite Scale of Morningness/Eveningness

You may not qualify if…

• Smoker
• Neurological, medical, or psychiatric disorder
• Diabetics
• History of eating disorders
• Sleep disorders
• Travel across time zones within 4 weeks of the study
• History of drug and alcohol abuse
• Shift worker
• Caffeine intake > 300 mg/d
• Excessive daytime sleepiness
• Regular napping
• History of drowsy driving
• Pregnancy or within 1 y post-partum
• Heavy equipment operator or commercial long-distance driver
• Contra-indications for MRI scanning

Where it is running

• Clinilabs — New York, New York, United States
• St. Luke's/Roosevelt Hospital — New York, New York, United States
• Columbia University — New York, New York, United States

Full record on ClinicalTrials.gov

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