Low Dose Extended-release Epidural and Lumbar Plexus Block Compared to Lumbar Plexus Block for Total Hip Resurfacing

Stopped early · Phase 4 · Has a placebo group

Conditions studied: Hip Arthroplasty

In brief

At Wake Forest University, the investigators have been using Extended Release Epidural Morphine (EREM), since late 2004, as part of multimodal analgesia in patients having gynecologic surgeries and hip arthroplasties. Hypothesis: In patients undergoing a Birmingham total hip arthroplasty (BHA), low dose EREM in conjunction with lumbar plexus block (LPB) will be better than lumbar plexus block alone in increasing proportion of patients who meet discharge criteria within 24 hours.

Key facts

Study ID

NCT00934661

Run by

Wake Forest University

People needed

40

Starts

2010-01-01

Expected to finish

2013-03-01

Last updated by the study team

2018-09-12

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• A primary unilateral Birmingham hip arthroplasty
• Men and women 18-65 years

You may not qualify if…

• Refusal of regional anesthesia
• Laboratory evidence of coagulopathy (platelet count less than 100,000 cells/microliter of blood, prothrombin time greater than 12.1 seconds, partial thromboplastin time greater than 30 seconds, or international normalized ratio of greater than 1.5)
• Allergy to morphine
• Obstructive sleep apnea
• Body mass index (BMI) greater than 40 kg/m2
• Pregnant or lactating
• Severe renal or hepatic disease

Where it is running

• Wake Forest University Baptist Medical Center — Winston-Salem, North Carolina, United States

Full record on ClinicalTrials.gov

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