Risk Factors for Implant Bone Loss in Patients With Diabetes Mellitus
Completed
Conditions studied: Diabetes
In brief
Dental implants are regarded as a standard of care in restoring missing teeth. Although there is a high prevalence of diabetics who receive dental implants, the relationship between dental implants and diabetes has not clearly been investigated. A total of 32 subjects (14 patients with type II diabetes and 18 non-diabetes subjects) who have dental implants were recruited. The purposes of this research study were: (1) to evaluate diabetes patients to determine risk factors for bone loss at dental implants and teeth; and (2) to evaluate bone-resorptive biomarkers (proteins related to bone loss) present in saliva and blood serum, comparing the two groups.
Key facts
- Study ID
- NCT00933491
- Run by
- University of Michigan
- People needed
- 32
- Starts
- 2008-11-01
- Expected to finish
- 2010-12-01
- Last updated by the study team
- 2015-11-04
Who can join
Age: 40 and older, up to 90. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- be at least 40 years old
- have at least one dental implant that has been in function for at least 6 months
- have at least 6 natural teeth
- have good general oral health
- not be pregnant or breastfeeding or planning to become pregnant within the next year
- if you are a pre-menopausal woman you or your male partner must be surgically sterile or you must be using reliable birth control (i.e., prescription oral contraceptives, contraceptive injections, intrauterine device, double-barrier method, contraceptive patch) now and throughout the study or abstain from sex throughout the study
You may not qualify if…
- not have an active oral infection, including periodontitis and rampant caries
- not have a history of chronic systemic illness or infection, history of oral cancer, life expectancy of less than 5 years
- not have had cancer treatment in the last 12 months
Where it is running
- Michigan Center for Oral Health Research — Ann Arbor, Michigan, United States
Full record on ClinicalTrials.gov
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