Neural Correlates of Cognitive Rehabilitation in Post-Traumatic Stress Disorder (PTSD)

Stopped early · Not applicable

Conditions studied: Post-Traumatic Stress Disorder

In brief

Post Traumatic Stress Disorder (PTSD) is an emotional disorder that can also lead to problems with attention and memory. Cognitive training has been successfully used to improve attention and processing speed in other patient populations as well as healthy elderly. The purpose of this study is to examine how effective cognitive training will be in Veterans with PTSD.

Key facts

Study ID

NCT00928941

Run by

US Department of Veterans Affairs

People needed

40

Starts

2010-05-01

Expected to finish

2011-12-01

Last updated by the study team

2014-12-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• OEF/OIF Veteran,
• meets DSM-IV criteria for PTSD,
• control group does not meet criteria for PTSD

You may not qualify if…

• prior history of significant head injury (LOC > 30 minutes) or other neurological disorder (e.g., stroke, seizure, multiple sclerosis), learning disability or confirmed diagnosis of ADHD,
• contraindication to MR imaging, failed malingering tests during testing, or a history of severe mental illness (i.e., Schizophrenia, Bipolar Disorder)
• individuals will be excluded if in the 30 days prior to the initial interview if they:
• do not have stable housing (i.e., staying in same residence),
• have medication changes or have had a psychiatric hospitalization,
• participants who meet DSM-IV criteria for substance dependence will be excluded from the study,
• individuals will also receive urine toxicology and Breathalyzer testing as the first procedure on the evaluation day (pre and post treatment and at 3 month follow up); participants who test positive for alcohol or recent substance use (e.g., methamphetamine) or report significant levels of drug or alcohol use if they are unable to abstain from substance use at three consecutive visits
• veterans who are currently engaged in therapy treatment for PTSD

Where it is running

• VA Connecticut Healthcare System West Haven Campus, West Haven, CT — West Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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