Early Identification of Subclinical Atherosclerosis Using Non-Invasive Imaging Research (EISNER)
Completed · Not applicable
Conditions studied: Atherosclerosis, Coronary Artery Disease
In brief
Early Identification of Subclinical Atherosclerosis by Noninvasive Imaging Research (EISNER) is a multi-study research program being conducted at Cedars-Sinai Medical Center. The principal objective of this randomized trial (referred to as "Study 1") is to assess whether coronary artery calcium (CAC) scanning provides clinical benefit thus improving patient outcomes in asymptomatic subjects with intermediate coronary artery disease (CAD) risk. Additionally, the study is designed to assess the value of combining the CAC scan with the Framingham risk score (FRS) and measurements of serum or plasma biomarkers to predict outcomes.
Key facts
- Study ID
- NCT00927693
- Run by
- Cedars-Sinai Medical Center
- People needed
- 2137
- Starts
- 2001-02-01
- Expected to finish
- 2010-08-01
- Last updated by the study team
- 2011-09-29
Who can join
Age: 45 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- No symptoms of CAD
- Intermediate risk of CAD, defined as either:
- male with age of 55-80 years or female with age 65-80 years or
- male of 45-54 years and at least one CAD risk factor or female with age 55-64 years and at least one CAD risk factor
- Risk factors include: smoking, high blood pressure, high total or LDL cholesterol, low HDL cholesterol, diabetes, family history of early CAD.)
You may not qualify if…
- History of CVD including heart attack, cardiomyopathy, peripheral artery disease, angina, revascularization, and CVA (stroke)
- Prior coronary calcium scan or coronary angiogram
- Pregnancy
- Required radiation badges for work (CSMC Radiation Safety ruling)
- Clinically unstable health status or significant medical co-morbidity
Where it is running
- Cedars-Sinai Medical Center — Los Angeles, California, United States
Full record on ClinicalTrials.gov
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