Compare the Clinical Efficacy of Prototype Toothpastes

Completed · Phase 3

Conditions studied: Dental Plaque

In brief

Clinical study to compare the clinical efficacy of toothpastes on dental plaque and gingival inflammation.

Key facts

Study ID

NCT00926029

Run by

Colgate Palmolive

People needed

98

Starts

2008-01-01

Expected to finish

2008-04-01

Last updated by the study team

2012-02-17

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male or female volunteers 18-65 years of age.
• Good general health.
• Must sign informed consent form.
• Minimum of 20 natural uncrowned teeth (excluding third molars) must be present.
• No history of allergy to personal care consumer products, or their ingredients, relevant to any ingredient in the test products as determined by the dental/medical professional monitoring the study.

You may not qualify if…

• Subject unable or unwilling to sign the informed consent form.
• Medical condition which requires pre-medication prior to dental visits/procedures.
• Moderate or advanced periodontal disease.
• 5 or more decayed untreated dental sites at screening.
• Other disease of the hard or soft oral tissues.
• Impaired salivary function (e.g. Sjogren's syndrome or head and neck irradiation).
• Use of medications that currently affect salivary flow.
• Use of antibiotics or antimicrobial drugs within 30 days prior to study visit #1.
• Pregnant or nursing women.
• Participation in any other clinical study within 1 week prior to enrollment into this study.
• Use of tobacco products.
• Subjects who must receive dental treatment during the study dates.
• Current use of Antibiotics for any purpose.
• Presence of an orthodontic appliance.
• History of allergy to common dentifrice ingredients.
• History of allergy to zinc.
• Immune compromised individuals (HIV, AIDS, immuno suppressive drug therapy).

Where it is running

• Concordia Clinical Research — Cedar Knolls, New Jersey, United States

Full record on ClinicalTrials.gov

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