Neurophysiological Targets for Cognitive Training in Schizophrenia

Completed · Not applicable

Conditions studied: Schizophrenia

In brief

The purpose of this study is to determine whether computer-based training of auditory and visual processing results in corresponding improvement in brain function in individuals with schizophrenia.

Key facts

Study ID

NCT00923078

Run by

VA Office of Research and Development

People needed

60

Starts

2010-11-01

Expected to finish

2014-10-01

Last updated by the study team

2017-12-22

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• DSM-IV diagnosis of schizophrenia or schizoaffective disorder
• Age between 18 \& 70
• minimum of 30 days since discharge from last hospitalization
• minimum of 30 days since last change in psychiatric medications
• receiving mental health services
• no housing changes in the past 30 days

You may not qualify if…

• current diagnosis of alcohol or substance abuse
• history of brain trauma or neurological disease
• chart diagnosis of mental retardation or premorbid intelligence < 70 based on Wechsler Test of Adult Reading (WTAR) full-scale estimated IQ
• auditory or visual impairment that would interfere with study procedures
• a sample of 20 healthy community volunteers was also recruited according to these criteria and tested, without intervention, as a normative reference sample for MMN and P300 measures

Where it is running

• VA Connecticut Health Care System (West Haven) — West Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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